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Calcium folinatc

Calcium folinate CAS No. : 6035-45-6


1. Basic information

Product name: Calcium folinate

Product Overview:

Calcium folinate, chemically known as N-[4-[(2-amino-5-formyl-1,4,5,6,7, 8-hexahydro-4-oxo-6-pteridinyl) methyl] amino-benzoyl-L-glutamate calcium salt, is an organic compound intended for use as an antidote and antianemia drug.

English name: Calcium folinatc

CAS No. : 6035-45-6

Molecular formula: C20H27CaN7O8

Molecular weight: 533.56

Physical and chemical properties: Melting point: 240-250℃ Appearance: yellow crystalline powder

2. Application
1. It is mainly used as an antidote to folate antagonists (such as methotrexate, pyrimethamine and trimethoprim, etc.), and is often used in clinical practice to prevent serious toxic effects caused by large doses or excessive treatment of methotrexate.
2. When folic acid is not effective in treating diseases such as oral diarrhea, protein-energy dystrophy (malnutrition), megaloblastic anemia caused by pregnancy or infancy
3. As an adjunct treatment for colon and rectal cancer
4. Combined with 5-FU for the treatment of digestive tract tumors or other 5-FU-sensitive tumors
5. It is used to rescue children leukemia, lymphoma, osteosarcoma and other high-dose MTX treatment

Key Word:

CAS No. : 6035-45-6

Calcium folinate

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©2022 Liaoning Jiahe Shengshi Pharmaceutical Technology Co.,Ltd. 

辽ICP备2021002629号 SEO