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Methotrexate disodium salt

Methotrexate disodium salt Content: 98.0%-102.0%

Description

Methotrexate disodium salt
Content: 98.0%-102.0%
Product Level: United States Pharmacopoeia (USP)
General parameters:
【CAS number 】7413-34-5
【 Molecular formula 】C20H20N8Na2O5
【 Molecular weight 】498.4
【EINECS number 】231-022-0
Methotrexate disodium salt
【 Packing 】25kg/ barrel
【 Storage 】 Keep in a cool and sealed place.

Product use:
Methotrexate, an organic compound, is mainly used as an anti-folate anti-tumor drug, which can inhibit the synthesis of tumor cells and inhibit the growth and reproduction of tumor cells by inhibiting dihydrofolate reductase.
Pharmacological action:
Tetrahydrofolate is an important coenzyme for the synthesis of purine nucleotides and pyrimidine deoxynucleotides in vivo. As a folate reductase inhibitor, this product mainly inhibits dihydrofolate reductase and prevents dihydrofolate from being reduced to tetrahydrofolate with physiological activity, thus blocking the transfer of carbon groups during the biosynthesis of purine nucleotides and pyrimidine nucleotides. The biosynthesis of DNA is inhibited. In addition, this product also has an inhibitory effect on thymus nucleotide synthase, but the inhibitory effect on RNA and protein synthesis is weak. This product mainly acts on the S phase of the cell cycle, which is a cell cycle specific drug. It also has a delayed effect on G1/S phase cells, but has a weak effect on G1 phase cells.
Packaging storage:
Keep in a cool and sealed place.

Key Word:

Methotrexate disodium salt Content: 98.0%-102.0%

7413-34-5


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©2022 Liaoning Jiahe Shengshi Pharmaceutical Technology Co.,Ltd. 

辽ICP备2021002629号  web:300.cn jinzhou.300.cn SEO